This research investigates the efficacy and safety of Nicotinamide Mononucleotide (NMN) supplementation in healthy middle-aged adults.
The study, a randomized, multicenter, double-blind, placebo-controlled clinical trial, specifically examines how NMN impacts blood NAD concentration, physical performance, biological age, insulin sensitivity, and overall health over a 60-day period. Researchers administered daily oral doses of 300 mg, 600 mg, or 900 mg of NMN, comparing the results against a placebo group.
The findings suggest that NMN significantly increases NAD levels and positively influences physical endurance and general health, with a 600 mg dose appearing to achieve maximum efficacy without additional benefits from a higher 900 mg dose, and importantly, no safety concerns were identified within the trial.
