Neuroprotection, mitochondrial stabilization, and longevity
in one capsule

An experimental, premium-class molecule that protects your brain, enhances mitochondria, and stays ahead of its time. A limited batch for health pioneers.

Pharma-grade purity validated by preclinical data

About

Precisely engineered CMS-121 molecule with ≥98% purity

Based on over a decade of research into neurodegeneration, mitochondrial fatigue, and oxidative stress, NEURO121 doesn’t just protect neurons — it lays new foundations for your cognitive performance.

Unmatched molecular precision

Advanced neuroprotection

Mitochondrial
power boost

Mitochondrial power boost

Next - level
longevity

Next - level longevity

Not for everyone

For minds that lead, decide, and perform under pressure

High-level decision makers

For leaders managing capital, teams, and critical decisions — requiring clarity, cognitive agility, and emotional resilience under constant pressure.

Longevity pioneers & conscious biohackers

For those who’ve moved beyond generic supplements and seek molecular tools that support brain health at the cellular level — precisely, measurably, and sustainably.

Early cognitive prevention

For individuals noticing early signs of mental fatigue, lapses in focus, or slight memory gaps. They don’t wait for decline — they intervene early and intelligently.

n=1 explorers

For independent, data-driven individuals. Self-experimenters with access to knowledge and readiness to explore what’s next — before the mainstream arrives.

The hidden cost of cognitive overload

74%

of senior leaders report that mental fatigue reduces decision quality later in the day.

62%

of knowledge professionals admit they experience frequent brain fog — despite sleep and supplementation.

89%

of nootropic users say their effects are short-lived and increasingly dependent on higher doses.

Advantage

3x higher bioavailability than fisetin

Optimized molecular design ensures stability, sustained bioactivity, and blood–brain barrier penetration.

0% habituation
0% stimulation

CMS-121 molecule with ≥98% purity, tested in independent laboratories. No fillers, no compromises.

Developed by Harvard University graduates

CMS-121 is the outcome of cutting-edge research into neurodegeneration and brain aging.

Beyond the ordinary - Neuro121’s edge

72%

Professionals note improved decision-making under pressure after incorporating NEURO121 into their routine.

85%

Users report sharper focus and mental clarity within the first 30 days of using NEURO121.

Advanced bioavailability

Optimized structure enables it to reach deep brain regions, outperforming standard fisetin. Proven effects in neurodegeneration models.

Aging isn’t a problem.
It’s a process. And every
process can be optimized.

Aging isn’t a problem.
It’s a process. And every process can be optimized.

Up to

95%

reduction in oxidative stress markers demonstrated in preclinical studies.

Mechanism

A five-step process to shield, energize, and future-proof your brain

Here’s how NEURO121 works to give you a cognitive edge—today and for decades to come.

Step 1

Crosses the blood-brain barrier for targeted, precision action

Most supplements work on the surface, never reaching where true neuroprotection begins. NEURO121 penetrates deep brain structures like the hippocampus and limbic system—key regions responsible for memory, emotions, and focus.

Step 2

Reduction of oxidative stress and neuroinflammation

Activates antioxidant enzymes such as SIRT1, which protect neuronal DNA from damage, and inhibits overactivity of microglia—the cells responsible for inflammation in the brain.

Step 3

Empowering your cellular power plants

NEURO121 enhances electron flow in the mitochondrial respiratory chain, prevents fragmentation of their structure, and protects mitochondrial membranes from lipid peroxidation.

Step 4

Support for neuroplasticity and cognitive function

Increases the expression of neurotrophic factors such as BDNF (brain-derived neurotrophic factor), which supports the growth and differentiation of neurons.

Step 5

Long-term protection and senolytic action

As a senolytic, NEURO121 helps eliminate aging cells (so-called zombie cells) that accumulate with age and trigger inflammation. At the same time, it activates longevity-associated pathways such as AMPK and PGC-1α.

Longevity code starts with 121

Benchmark

Is second to none

Not every nootropic works at the cellular level. Not every compound supports mitochondria, neuroplasticity, and longevity at the same time. And certainly, not every one has evolved from neurodegeneration research into an advanced bioactive molecule with ≥98% purity.

Property	Neuro121 CMS	Neuro NAD+	Fisetin	NR (Niagen)	Resveratrol	Spermidine	Caffeine
Neuroprotection	+ + +	+ +	+ +	+ +	+	+	-
Support for memory and concentration	+ + +	+	+	+	+ +	-	+ +
Slowing down neuronal aging	+ + +	+ +	+ +	+	+	+	-
Impact on NAD+ levels	-	+ + +	-	+ + +	-	-	-
Mitochondrial function	+ +	+ +	+	+ +	+	+ +	-
Reduction of oxidative stress	+ + +	+ +	+ +	+	+ +	+	-
Anti-inflammatory properties	+ + +	+	+ +	+	+ +	+ +	-
Long-term effect (longevity)	+ + +	+ +	+ +	+ +	+ +	+ + +	-
On-demand energy effect	+	+	-	+	-	-	+ + +
Safe for long-term use	+ + +	+ +	+ + +	+ +	+ +	+ + +	+
Natural bioavailability	+ +	+	+	+	-	+	+ + +
Support in research on neurodegenerative diseases	+ + +	+	+ +	+	+	+	-
Metabolic health and glucose regulation	+ + +	-	-	-	-	-	-
Support in diabetes and insulin resistance	+ + +	-	-	-	-	-	-
Impact on obesity and weight management	+ + +	-	-	-	-	-	-
Hi-End Level	92%	67%	60%	57%	50%	50%	27%

Testimonials

Expert endorsements,
user perspectives

Dr. Sarah Lawrence 🇺🇸

Molecular Neurologist, California

What excites me about CMS-121 is that it doesn't follow the traditional path of cognitive enhancers - it doesn't flood the brain with stimulants or attempt to hack neurotransmitters. Instead, it reinforces the structural and energetic foundation of neurons. We're talking about mitochondrial stabilization, anti-inflammatory modulation, and molecular senolytics - real cellular impact. In my view, it's the most promising direction in non-pharmaceutical neuroprotection.

Most cognitive enhancers wear off or backfire. NEURO121 didn't fade - it compounded. Week after week I felt less reactive, more centered, and far more efficient. This is what biohacking should have been all along.

Anders 🇳🇴

Lead Cybersecurity Analyst, Oslo

I need execution. With NEURO121, I recover mental bandwidth faster, think longer without friction, and stop chasing quick-fix stacks. It's now part of my protocol, like NMN and sleep tracking.

Élise 🇫🇷

Medtech entrepreneur, Paris

I work across five time zones, constantly under decision-making pressure. NEURO121 gave me something no other nootropic ever did: cognitive stability that holds even under decision fatigue. No artificial stimulation-just pure clarity.

Martin 🇩🇪

Strategic Advisor, Frankfurt

The code of longevity begins with 121 - CMS

Neuro121^CMS

CMS121 targets cellular aging, energy metabolism, and oxidative stress at the mitochondrial level – supporting brain health and cognitive longevity.

This exclusive early release is strictly limited. Take advantage of priority access with a one-time offer reserved for early adopters. Available until the limited allocation is exhausted.

CMS121 / 100 mg

€89

Free courier shipping
100% pure ingredients

Cognitive longevity - enhanced NAD+

Neuro121^NAD

Liposomal NAD+ in microencapsulated form, supporting mitochondrial biogenesis essential for cellular energy and DNA repair.

Increases NAD+ levels - essential for mitochondrial function and DNA repair
Promotes the formation of new mitochondria and boosts cellular energy
Protects neurons and cardiac cells from oxidative stress
May enhance memory, reaction time, sleep quality, and physical recovery

Liposomal NAD+ 60 caps / 250 mg – microencapsulated

€49

Free courier shipping
100% pure ingredients

Insights

Get inspired by knowledge that transforms the approach to neurological health and longevity.

Understand the foundations of brain health and longevity to invest consciously in your future. The latest trends and insights for biohackers and leaders who want to stay ahead of their time. Stay up to date with the newest developments and discoveries in the world of NEURO121.

Contact

Start with a question.
Continue with results.

Get in touch

Whether you’re running a protocol, seeking integration advice, or want to understand if NEURO121 fits your current stack — speak to us directly.

Write to us

contact@neuro-121.com

Fill out the contact form

By submitting this form you agree to our Privacy Policy. Optimum may contact you via email or phone for scheduling or marketing purposes.

Important notes

Everything you need to know before starting the NEURO121 protocol

White paper

Detailed overview of NEURO121, CMS-121, and the science behind cognitive and mitochondrial protection.

Legal disclaimer

Essential legal information on the experimental status and responsible use of NEURO121.

Usage & form

Capsule specs, dosing guidance, and compatibility with longevity stacks.

Swiss Quality Testing Report

Independent lab results confirming CMS-121 purity, stability, and safety.

n=1 Monitoring Protocol

Self-tracking framework for users following personalized NEURO121 protocols.

n=1 Blood Test Sheet

Suggested biomarker panel for pre- and post-cycle lab testing.

Neuroprotection, mitochondrial stabilization, and longevity in one capsule

An experimental, premium-class molecule that protects your brain, enhances mitochondria, and stays ahead of its time. A limited batch for health pioneers.

Pharma-grade purity validated by preclinical data

Precisely engineered CMS-121 molecule with ≥98% purity

Unmatched molecular precision

Advanced neuroprotection

Mitochondrial power boost

Mitochondrial power boost

Next - level longevity

Next - level longevity

For minds that lead, decide, and perform under pressure

High-level decision makers

Longevity pioneers & conscious biohackers

Early cognitive prevention

n=1 explorers

74%

62%

89%

3x higher bioavailability than fisetin

0% habituation 0% stimulation

Developed by Harvard University graduates

Beyond the ordinary - Neuro121’s edge

Advanced bioavailability

Aging isn’t a problem. It’s a process. And every process can be optimized.

Aging isn’t a problem. It’s a process. And every process can be optimized.

A five-step process to shield, energize, and future-proof your brain

Is second to none

Expert endorsements, user perspectives

Dr. Sarah Lawrence 🇺🇸

Anders 🇳🇴

Élise 🇫🇷

Martin 🇩🇪

The code of longevity begins with 121 - CMS

Neuro121 CMS

CMS121 / 100 mg

€89

Cognitive longevity - enhanced NAD+

Neuro121 NAD

€49

Get inspired by knowledge that transforms the approach to neurological health and longevity.

Start with a question. Continue with results.

Get in touch

Write to us

Fill out the contact form

Everything you need to know before starting the NEURO121 protocol

White paper

Legal disclaimer

Usage & form

Swiss Quality Testing Report

n=1 Monitoring Protocol

n=1 Blood Test Sheet

Stay Ahead.

Subscribe for Expert Insights.

Neuroprotection, mitochondrial stabilization, and longevity
in one capsule

Mitochondrial
power boost

Next - level
longevity

0% habituation
0% stimulation

Aging isn’t a problem.
It’s a process. And every
process can be optimized.

Aging isn’t a problem.
It’s a process. And every process can be optimized.

Expert endorsements,
user perspectives

Neuro121^CMS

Neuro121^NAD

Start with a question.
Continue with results.