Neuroprotection, mitochondrial stabilization, and longevity
in one capsule

An experimental, premium-class molecule that protects your brain, enhances mitochondria, and stays ahead of its time. A limited batch for health pioneers.
Deeper knowledge ahead
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Pharma-grade purity validated by preclinical data
  • Swiss Lab independently tested
  • Crafted in European Union
About

Precisely engineered CMS-121 molecule with ≥98% purity

Based on over a decade of research into neurodegeneration, mitochondrial fatigue, and oxidative stress, NEURO121 doesn’t just protect neurons — it lays new foundations for your cognitive performance.

Unmatched molecular precision

  • Engineered with ≥98% purity, free from fillers or impurities.
  • Tested in independent labs for unmatched quality.
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Advanced neuroprotection

  • Shields neurons from oxidative damage and inflammation.
  • Inspired by Salk Institute’s cutting-edge research.
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Mitochondrial
power boost

Mitochondrial power boost

  • Optimizes cellular energy to eliminate fatigue.
  • Enhances mental clarity for peak performance.
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Next - level
longevity

Next - level longevity

  • Targets aging cells with senolytic action
  • Designed for those who plan decades ahead.
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Not for everyone

For minds that lead, decide, and perform under pressure

High-level decision makers

For leaders managing capital, teams, and critical decisions — requiring clarity, cognitive agility, and emotional resilience under constant pressure.

Longevity pioneers & conscious biohackers

For those who’ve moved beyond generic supplements and seek molecular tools that support brain health at the cellular level — precisely, measurably, and sustainably.

Early cognitive prevention

For individuals noticing early signs of mental fatigue, lapses in focus, or slight memory gaps. They don’t wait for decline — they intervene early and intelligently.

n=1 explorers

For independent, data-driven individuals. Self-experimenters with access to knowledge and readiness to explore what’s next — before the mainstream arrives.

The hidden cost of cognitive overload
74%

of senior leaders report that mental fatigue reduces decision quality later in the day.

62%

of knowledge professionals admit they experience frequent brain fog — despite sleep and supplementation.

89%

of nootropic users say their effects are short-lived and increasingly dependent on higher doses.

Advantage

3x higher bioavailability than fisetin

Optimized molecular design ensures stability, sustained bioactivity, and blood–brain barrier penetration.

Understand the mechanism

0% habituation
0% stimulation

CMS-121 molecule with ≥98% purity, tested in independent laboratories. No fillers, no compromises.

Developed by Harvard University graduates

CMS-121 is the outcome of cutting-edge research into neurodegeneration and brain aging.

Beyond the ordinary - Neuro121’s edge
72%

Professionals note improved decision-making under pressure after incorporating NEURO121 into their routine.

85%

Users report sharper focus and mental clarity within the first 30 days of using NEURO121.

Advanced bioavailability

Optimized structure enables it to reach deep brain regions, outperforming standard fisetin. Proven effects in neurodegeneration models.

Aging isn’t a problem.
It’s a process. And every
process can be optimized.

Aging isn’t a problem.
It’s a process. And every process can be optimized.

Up to
95%
reduction in oxidative stress markers demonstrated in preclinical studies.
Master your day with NEURO121
Mechanism

A five-step process to shield, energize, and future-proof your brain

Here’s how NEURO121 works to give you a cognitive edge—today and for decades to come.

Step 1
Crosses the blood-brain barrier for targeted, precision action

Most supplements work on the surface, never reaching where true neuroprotection begins. NEURO121 penetrates deep brain structures like the hippocampus and limbic system—key regions responsible for memory, emotions, and focus.

Step 2
Reduction of oxidative stress and neuroinflammation

Activates antioxidant enzymes such as SIRT1, which protect neuronal DNA from damage, and inhibits overactivity of microglia—the cells responsible for inflammation in the brain.

Step 3
Empowering your cellular power plants

NEURO121 enhances electron flow in the mitochondrial respiratory chain, prevents fragmentation of their structure, and protects mitochondrial membranes from lipid peroxidation.

Step 4
Support for neuroplasticity and cognitive function

Increases the expression of neurotrophic factors such as BDNF (brain-derived neurotrophic factor), which supports the growth and differentiation of neurons.

Step 5
Long-term protection and senolytic action

As a senolytic, NEURO121 helps eliminate aging cells (so-called zombie cells) that accumulate with age and trigger inflammation. At the same time, it activates longevity-associated pathways such as AMPK and PGC-1α.

Longevity code starts with 121
Benchmark

Is second to none

Not every nootropic works at the cellular level. Not every compound supports mitochondria, neuroplasticity, and longevity at the same time. And certainly, not every one has evolved from neurodegeneration research into an advanced bioactive molecule with ≥98% purity.

PropertyCMS121NMNResveratrolCaffeineFisetinSpermidineNR (Niagen)
Neuroprotection+ + ++ ++-+ +++ +
Support for memory and concentration+ + +++ ++ ++-+
Slowing down neuronal aging+ + ++ ++-+ +++
Impact on NAD+ levels-+ + +----+ + +
Mitochondrial function+ ++ ++-++ ++ +
Reduction of oxidative stress+ + ++ ++ +-+ +++
Anti-inflammatory properties+ + +++ +-+ ++ ++
Long-term effect (longevity)+ + ++ ++ +-+ ++ + ++ +
On-demand energy effect++-+ + +--+
Safe for long-term use+ + ++ ++ +++ + ++ + ++ +
Natural bioavailability+ ++-+ + ++++
Support in research on neurodegenerative diseases+ + +++-+ +++
Hi-End Level81%67%50%27%60%50%57%
Testimonials

Expert endorsements,
user perspectives

Verify it by yourself
Dr. Sarah Lawrence 🇺🇸
Molecular Neurologist, California
What excites me about CMS-121 is that it doesn’t follow the traditional path of cognitive enhancers — it doesn’t flood the brain with stimulants or attempt to hack neurotransmitters. Instead, it reinforces the structural and energetic foundation of neurons. We’re talking about mitochondrial stabilization, anti-inflammatory modulation, and molecular senolytics — real cellular impact. In my view, it’s the most promising direction in non-pharmaceutical neuroprotection.
Most cognitive enhancers wear off or backfire. NEURO121 didn’t fade — it compounded. Week after week I felt less reactive, more centered, and far more efficient. This is what biohacking should have been all along.
Anders 🇳🇴
Lead Cybersecurity Analyst, Oslo
I need execution. With NEURO121, I recover mental bandwidth faster, think longer without friction, and stop chasing quick-fix stacks. It’s now part of my protocol, like NMN and sleep tracking.
Élise 🇫🇷
Medtech entrepreneur, Paris
I work across five time zones, constantly under decision-making pressure. NEURO121 gave me something no other nootropic ever did: cognitive stability that holds even under decision fatigue. No artificial stimulation—just pure clarity.
Martin 🇩🇪
Strategic Advisor, Frankfurt

Choose how you begin

Access before the rest

Early access is a reserved channel for users ready to integrate NEURO121 before it hits wider availability. Limited batches. Priority shipping.

Your cycle starts before the protocol becomes public. Perfect for experienced nootropic users, n=1 researchers, and those who shape their biology — not follow trends.

$129

30 capsules per pack
Each capsule contains 100 mg CMS-121
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  • Guaranteed shipping starting from June 20
Number of units remaining ↓
1600

Run it, track it - decide for yourself

A full cycle — 30 capsules of pure CMS-121 — to test NEURO121 within your personal protocol. Ideal for professionals, skeptics, or conscious explorers who need to feel the shift before committing. 

$199

30 capsules per pack
Each capsule contains 100 mg CMS-121
Order now
Track what matters to you
Daily focus, sleep quality, stress response, or clarity under pressure — define your metrics. You’re not testing a hype. You’re testing your brain.
One box. One cycle. One insight.
30 days. 30 chances to know. No automatic reorder. No pressure. Just data you own.

Clarity isn’t a luxury. It’s infrastructure.

The subscription route ensures uninterrupted access to CMS-121. Priority batches, consistent dosing, and access to extended longevity protocols and expert resources.

$179

Subscribe & receive monthly:
30 capsules per month – each capsule contains 100 mg CMS-121
Subscribe now
Fresh molecule, every cycle
Automatic delivery every 30 days from the most recent CMS-121 production run. Stability. Consistency. No gaps, no guessing.
Access the n=1 underground
Join our private WhatsApp group and receive curated research drops, protocol updates, and direct links to new findings — before they go public.
Insights

Get inspired by knowledge that transforms the approach to neurological health and longevity.

Understand the foundations of brain health and longevity to invest consciously in your future. The latest trends and insights for biohackers and leaders who want to stay ahead of their time. Stay up to date with the newest developments and discoveries in the world of NEURO121.
CMS-121 in Alzheimer’s models: what the preclinical data reveals
Can a molecule inspired by strawberries help fight one of the most complex diseases of our time? CMS-121, a refined derivative of fisetin, shows promising neuroprotective effects in preclinical models of Alzheimer’s.
CMS-121 vs fisetin: what changes when science refines nature
Fisetin is a promising natural compound. Discover how science enhanced nature to create a molecule with superior bioavailability, deeper neuroprotective effects, and real potential in longevity protocols.
Neuroinflammation: the silent enemy behind brain fog and burnout
Brain fog, burnout, poor sleep and heightened reactivity aren’t always signs of stress or lifestyle imbalance. Often, they signal a deeper biological disruption: low-grade neuroinflammation.
How CMS-121 modulates AMPK and SIRT1 – a look into energy longevity pathways
Discover how CMS-121 activates these longevity pathways to support mitochondrial health, reduce inflammation, and slow neurological aging — from the inside out.
Contact

Start with a question.
Continue with results.

Get in touch
Whether you’re running a protocol, seeking integration advice, or want to understand if NEURO121 fits your current stack — speak to us directly.
Write to us

contact@neuro-121.com

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Important notes

Everything you need to know before starting the NEURO121 protocol

Do you have question?
White paper

Detailed overview of NEURO121, CMS-121, and the science behind cognitive and mitochondrial protection.

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Legal disclaimer

Essential legal information on the experimental status and responsible use of NEURO121.

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Usage & form

Capsule specs, dosing guidance, and compatibility with longevity stacks.

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Swiss Quality Testing Report

Independent lab results confirming CMS-121 purity, stability, and safety.

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n=1 Monitoring Protocol

Self-tracking framework for users following personalized NEURO121 protocols.

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n=1 Blood Test Sheet

Suggested biomarker panel for pre- and post-cycle lab testing.

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