Neuroprotection, mitochondrial stabilization, and longevity
in one capsule

An experimental, premium-class molecule that protects the brain, enhances mitochondria, and stays ahead of its time. A limited batch for early testing.
Deeper knowledge ahead
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  • Swiss Lab independently tested
  • Crafted in European Union
About

Precisely engineered CMS-121 molecule with ≥98% purity

Based on over a decade of research into neurodegeneration, mitochondrial fatigue, and oxidative stress, NEURO121 doesn’t just protect neurons — it lays new foundations for your cognitive performance.

Unmatched molecular precision

  • Engineered with ≥98% purity, free from fillers or impurities.
  • Tested in independent labs for unmatched quality.
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Advanced neuroprotection

  • Shields neurons from oxidative damage and inflammation.
  • Inspired by Salk Institute’s cutting-edge research.
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Mitochondrial
power boost

Mitochondrial power boost

  • Optimizes cellular energy to eliminate fatigue.
  • Enhances mental clarity for peak performance.
Learn More

Next - level
longevity

Next - level longevity

  • Targets aging cells with senolytic action
  • Designed for those who plan decades ahead.
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The hidden cost of cognitive overload
74%

of senior leaders report that mental fatigue reduces decision quality later in the day.

62%

of knowledge professionals admit they experience frequent brain fog — despite sleep and supplementation.

89%

of nootropic users say their effects are short-lived and increasingly dependent on higher doses.

Aging isn’t a problem.
It’s a process. And every
process can be optimized.

Aging isn’t a problem.
It’s a process. And every process can be optimized.

Up to
95%
reduction in oxidative stress markers demonstrated in preclinical studies.
Master your day with NEURO121
Mechanism

A five-step process to shield, energize, and future-proof your brain

Here’s how NEURO121 works to give you a cognitive edge—today and for decades to come.

Step 1
Crosses the blood-brain barrier for targeted, precision action

Most supplements work on the surface, never reaching where true neuroprotection begins. NEURO121 penetrates deep brain structures like the hippocampus and limbic system—key regions responsible for memory, emotions, and focus.

Step 2
Reduction of oxidative stress and neuroinflammation

Activates antioxidant enzymes such as SIRT1, which protect neuronal DNA from damage, and inhibits overactivity of microglia—the cells responsible for inflammation in the brain.

Step 3
Empowering your cellular power plants

NEURO121 enhances electron flow in the mitochondrial respiratory chain, prevents fragmentation of their structure, and protects mitochondrial membranes from lipid peroxidation.

Step 4
Support for neuroplasticity and cognitive function

Increases the expression of neurotrophic factors such as BDNF (brain-derived neurotrophic factor), which supports the growth and differentiation of neurons.

Step 5
Long-term protection and senolytic action

As a senolytic, NEURO121 helps eliminate aging cells (so-called zombie cells) that accumulate with age and trigger inflammation. At the same time, it activates longevity-associated pathways such as AMPK and PGC-1α.

Longevity code starts with 121

First edition –
the code of longevity begins with 121

Access before the rest

Early access is a reserved channel for users ready to integrate NEURO121 before it hits wider availability. Limited batches. Priority shipping.

Your cycle starts before the protocol becomes public. Perfect for experienced nootropic users, n=1 researchers, and those who shape their biology — not follow trends.

$89

30 capsules per pack
Each capsule contains 50 mg CMS-121
Order now
Limited First Edition + Free shipping
This exclusive early release is strictly limited. Take advantage of priority access with a one-time offer reserved for early adopters. Available until the limited allocation is exhausted.
Number of units remaining ↓
500

Coming this fall -
explore our autumn 2025 picks

Neuro X - unique NMN - based formula

Each capsule delivers 50 mg CMS121 and 150 mg NMN — a synergy targeting the biological roots of aging, fatigue, and neurodegeneration.

  • NAD⁺ meets neuroprotection – NMN restores NAD⁺ levels while CMS121 leverages them to activate cellular repair and energy pathways.
  • Mitochondrial resilience – Enhances ATP production and reduces oxidative stress in neurons.

Neuro Q - advanced PQQ - powered formula

This dual-action formula unites 50 mg CMS121 and 10 mg PQQ in one capsule — engineered to enhance mitochondrial health, stimulate neuroregeneration, and ignite cellular resilience.

  • Dual pathway action – CMS121 shields and optimizes existing mitochondria, while PQQ drives the creation of new ones (biogenesis).
  • Deep brain effects – Supports the hippocampus and limbic structures under oxidative stress and chronic fatigue.
Ask about the product
Insights

Get inspired by knowledge that transforms the approach to neurological health and longevity.

Understand the foundations of brain health and longevity to invest consciously in your future. The latest trends and insights for biohackers and leaders who want to stay ahead of their time. Stay up to date with the newest developments and discoveries in the world of NEURO121.
Podcast – Inside Neuro121 – molecule redefining longevity
In this deep-dive conversation, we explore the science, potential, and real-world impact of NEURO121 — an experimental molecule designed for cognitive longevity. If you care about brain health, mental clarity...
CMS-121 in Alzheimer’s models: what the preclinical data reveals
Can a molecule inspired by strawberries help fight one of the most complex diseases of our time? CMS-121, a refined derivative of fisetin, shows promising neuroprotective effects in preclinical models of Alzheimer’s.
Beyond GLP-1: How CMS121 could transform weight loss therapy
CMS121, while originally developed for neurodegeneration, may also offer a novel metabolic advantage—one that mimics the benefits of fasting and ketosis at the molecular level.
CMS-121 vs fisetin: what changes when science refines nature
Fisetin is a promising natural compound. Discover how science enhanced nature to create a molecule with superior bioavailability, deeper neuroprotective effects, and real potential in longevity protocols.
Neuroinflammation: the silent enemy behind brain fog and burnout
Brain fog, burnout, poor sleep and heightened reactivity aren’t always signs of stress or lifestyle imbalance. Often, they signal a deeper biological disruption: low-grade neuroinflammation.
How CMS-121 modulates AMPK and SIRT1 – a look into energy longevity pathways
Discover how CMS-121 activates these longevity pathways to support mitochondrial health, reduce inflammation, and slow neurological aging — from the inside out.
Important notes

Everything you need to know before starting the NEURO121 protocol

Do you have question?
White paper

Detailed overview of NEURO121, CMS-121, and the science behind cognitive and mitochondrial protection.

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Legal disclaimer

Essential legal information on the experimental status and responsible use of NEURO121.

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Usage & form

Capsule specs, dosing guidance, and compatibility with longevity stacks.

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Swiss Quality Testing Report

Independent lab results confirming CMS-121 purity, stability, and safety.

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Certificate of Analysis

Verified laboratory data confirming batch-specific identity, purity, and potency of NEURO121.

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n=1 Monitoring Protocol

Self-tracking framework for users following personalized NEURO121 protocols.

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Contact

Start with a question.
Continue with results.

Get in touch
Whether you’re running a protocol, seeking integration advice, or want to understand if NEURO121 fits your current stack — speak to us directly.
Write to us

contact@neuro-121.com

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